- Sauquoit, New York
- Savannah, Georgia
- Scarsdale, New York
- Schaumburg, Illinois
- Schenectady, New York
- Scotch Plains, New Jersey
- Scotts Valley, California
- Scottsdale, Arizona
- Scranton, Pennsylvania
- Sea Island, Georgia
- Seagrove Beach, Florida
- Seal Beach, California
- Searcy, Arkansas
- Seaside, California
- Seattle, Washington
- Sebago, Maine
- Sedalia, Colorado
- Sedona, Arizona
- Senath, Missouri
- Seneca, South Carolina
- Sevierville, Tennessee
- Sewanee, Tennessee
- Shakopee, Minnesota
- Sharpsburg, Georgia
- Shawnee, Oklahoma
- Sheboygan, Wisconsin
- Sheffield, Iowa
- Shelby, Michigan
- Shelbyville, Tennessee
- Shell Knob, Missouri
- Shelter Island, New York
- Sheridan, Colorado
- Sherman, Texas
- Short Hills, New Jersey
- Shreveport, Louisiana
- Sidman, Pennsylvania
- Siloam Springs, Arkansas
- Silver City, New Mexico
- Silverton, Oregon
- Skokie, Illinois
