- Snellville, Georgia
- Snowbird, Utah
- Snowmass, Colorado
- Snyder, Texas
- Solon, Ohio
- Somerset County, New Jersey
- Somerset, Kentucky
- Somerset, Pennsylvania
- Somerville, Massachusetts
- Somerville, Tennessee
- South Charleston, West Virginia
- South Chesterfield, Virginia
- South Elgin, Illinois
- South Gate, California
- South Haven, Michigan
- South Holland, Illinois
- South Kingstown, Rhode Island
- South Norwalk, Connecticut
- South Padre Island, Texas
- South Salt Lake, Utah
- South Sioux City, Nebraska
- Southampton, New York
- Southaven, Mississippi
- Southborough, Massachusetts
- Southlake, Texas
- Sparks, Nevada
- Sparks, Oklahoma
- Spartanburg, South Carolina
- Spicewood, Texas
- Splendora, Texas
- Spring Hill, Tennessee
- Spring Valley, New York
- Spring, Texas
- Springdale, Arkansas
- Springdale, Utah
- Springfield, Illinois
- Springfield, Missouri
- Springtown, Texas
- Squaw Valley, California
- St. Amant, Louisiana
